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Ready-to-Use Embedded Control System for DNA Sequence Replication


Industry Molecular Diagnostics
   
Application Area Embedded Control
   
Date November 2009

Challenge

Controlling and maintaining an environment which requires precise temperature changes and sensor control in order to complete DNA reactions, while monitoring the process with a touch-screen user interface (UI).

Solution

Using Circaflex Developer Suite to develop and build a system within three days that included most of the required sensors and a simple, straightforward HMI for system control. 


Researchers at Nexogen created a polymerase chain reaction (PCR) machine to specialize in molecular diagnostics. PCR is a scientific process in which researchers are able to replicate a specific DNA sequence. This technique is used most commonly in diagnostics for hereditary and infectious diseases, forensic research, and paternal testing. The process involves the repeated heating and cooling of the DNA environment to have a successful cloning reaction.

The PCR machine from Nexogen required various process management devices including:
        • Stepper motors
        • Thermoelectric cooling devices
        • RTDs
        • High-intensity LEDs
        • Galvanometer
        • Laser diodes
        • Fans
        • Peltiers
        • Heat sinks
        • Heaters
        • Safety interlock sensor
        • Touch-screen monitor

Within a few weeks, the Nexogen system was running with all required sensors. Product developers, from university researchers and chemists to electrical and biomedical engineers, can use Circaflex to deliver critical, high-speed control without the need for costly and time-consuming custom FPGA programming. The Circaflex package includes the use of pre-developed software executables required for the real-time operating system (RTOS), FPGA, and HMI. These features give developers efficiency gains to stay on schedule and reduce risk in their projects with a customizable COTS device.

Customer Quote
“With Circaflex, it took only 15 days for us to achieve a working system that included all our necessary, customized I/O. Building a control board with custom products would have taken five times as long and cost at least five times as much as what we created with Circaflex.”

- Dalibor Hodko, CEO of Nexogen


Next Steps

Contact Cyth Systems to learn how Circaflex can speed up your product development

See More
Circaflex Case Study - Using Circaflex Development Suite for Rapid Medical Device Testing
Circaflex Case Study - PBS Biotech Uses Circaflex Development Suite to Cultivate Live Cells


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